Cerebral small vessel disease and Alzheimer's disease.

摘要: Cerebral small vessel disease (CSVD) is a group of pathological processes with multifarious etiology and pathogenesis that are involved into the arteries, arterioles, venules, capillaries brain. CSVD mainly contains lacunar infarct or stroke, leukoaraiosis, Binswanger's disease, cerebral microbleeds. an important microvascular as it cause 20% strokes worldwide most common cognitive impairment dementia, including vascular dementia Alzheimer's (AD). It has been well identified contributes to occurrence AD. seems treatment prevention for cerebrovascular diseases statins have such role in same function So far, there no strong evidence-based medicine support idea, although increasing basic studies supported fact will benefit Furthermore, still lack evidence clinical application specific drugs both AD CSVD.