Making Sense of the Sensory Lineage

作者: Marianne Bronner-Fraser

DOI: 10.1126/SCIENCE.1094732

关键词: BiologyLineage (genetic)Wnt signaling pathwaySense (molecular biology)Neural crestGeneticsEmbryoCell typeNeuroscienceSensory system

摘要: Neural crest cells are multipotent stem cell-like precursors that give rise to many different cell types in the developing embryo. In her Perspective, Bronner-Fraser discusses new research ( Lee et al.) identifies Wnt signaling pathway as developmental instruction directing neural become sensory neurons.

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