The efficacy of a single daily dose of enoxaparin for deep vein thrombosis prophylaxis following total knee arthroplasty.
作者： Pamela A Pulido , Steven N Copp , Richard H Walker , Lianette M Reden , Mary E Hardwick
DOI: 10.3928/0147-7447-20041101-16
关键词: Arthroplasty 、 Deep vein 、 Prosthesis 、 Cohort study 、 Medicine 、 Anesthesia 、 Asymptomatic 、 Low molecular weight heparin 、 Thrombosis 、 Surgery 、 Anticoagulant
摘要: Deep vein thrombosis (DVT) is a major risk following total knee arthroplasty (TKA). This prospective outcomes study evaluates the efficacy of enoxaparin 40 mg once daily for 7 days after TKA, by documenting symptomatic and asymptomatic using bilateral lower extremity duplex ultrasound upon hospital discharge on postoperative day 21 (+/-2). In 60 extremities, demonstrated DVT prevalence 16.7% (10) 11.7% (7) 21. No new or propagation distal to proximal were noted. For this small cohort, demonstrates effective prophylaxis in TKA patients.
wyanokecdn.com 参考文章(12)
Andrè Planes, Nicole Vochelle, Frçngois Mazas, Christian Mansat, Jean Zucman, Alain Landais, Jean Claude Pascariello, Dan Weill, Butel Jean, Prevention of postoperative venous thrombosis: a randomized trial comparing unfractionated heparin with low molecular weight heparin in patients undergoing total hip replacement. Thrombosis and Haemostasis. ,vol. 60, pp. 407- 410 ,(1988) , 10.1055/S-0038-1646980
Colwell Cw, Ritter Ma, Trowbridge Aa, Spiro Te, Stephens Jw, Gardiner Ga, Efficacy and safety of enoxaparin versus unfractionated heparin for prevention of deep venous thrombosis after elective knee arthroplasty. Enoxaparin Clinical Trial Group. Clinical Orthopaedics and Related Research. pp. 19- 27 ,(1995)
Andrew W. Howard, Shawn D. Aaron, Low molecular weight heparin decreases proximal and distal deep venous thrombosis following total knee arthroplasty : A meta-analysis of randomized Trials Thrombosis and Haemostasis. ,vol. 79, pp. 902- 906 ,(1998) , 10.1055/S-0037-1615090
Clive Kearon, Jack Hirsh, The diagnosis of pulmonary embolism. Haemostasis. ,vol. 25, pp. 72- 87 ,(1995) , 10.1159/000217145
David Bergqvist, John A. Heit, Michael R. Lassen, Joel C. Ray, Willitim Geerts, Graham F. Pineo, Clifford W. Colwell, Prevention of Venous Thromboembolism ,(1994)
Clifford W. Colwell, Theodore E. Spiro, Arthur A. Trowbridge, James W.G. Stephens, Geoffrey A. Gardiner, Merrill A. Ritter, Efficacy and Safety of Enoxaparin Versus Unfractionated Heparin for Prevention of Deep Venous Thrombosis After Elective Knee Arthroplasty Clinical Orthopaedics and Related Research. ,vol. 321, pp. 19- 27 ,(1995) , 10.1097/00003086-199512000-00004
André Planes, Nicole Vochelle, Jean-Yves Darmon, Michel Fagola, Michel Bellaud, Yann Huet, Risk of deep-venous thrombosis after hospital discharge in patients having undergone total hip replacement: double-blind randomised comparison of enoxaparin versus placebo The Lancet. ,vol. 348, pp. 224- 228 ,(1996) , 10.1016/S0140-6736(96)01453-5
John A. Heit, Prevention of venous thromboembolism. Clinics in Geriatric Medicine. ,vol. 17, pp. 71- 92 ,(2001) , 10.1016/S0749-0690(05)70107-5
J C Grady-Benson, C S Oishi, P B Hanson, C W Colwell, S M Otis, R H Walker, Postoperative surveillance for deep venous thrombosis with duplex ultrasonography after total knee arthroplasty. Journal of Bone and Joint Surgery, American Volume. ,vol. 76, pp. 1649- 1657 ,(1994) , 10.2106/00004623-199411000-00008
P Faunø, O Suomalainen, V Rehnberg, T B Hansen, K Krøner, S Soimakallio, E Nielsen, Prophylaxis for the prevention of venous thromboembolism after total knee arthroplasty. A comparison between unfractionated and low-molecular-weight heparin. Journal of Bone and Joint Surgery, American Volume. ,vol. 76, pp. 1814- 1818 ,(1994) , 10.2106/00004623-199412000-00007