Anaphylaxis to apple: is fasting a risk factor for LTP-allergic patients?
作者： Arena A
DOI:
关键词: Anaphylaxis 、 Food allergy 、 Gastrointestinal tract 、 Medicine 、 Allergy 、 Allergen 、 Ingestion 、 Immunology 、 Pepsin 、 Plant lipid transfer proteins
摘要: Background: Primary apple allergy is frequent in Mediterranean countries where hypersensitivity to lipid transfer protein (LTP) common. Due its stability upon pepsin digestion, L TP may cause systemic allergic reactions. This study investigated the potential risk associated with an isolated intake of while fasting LTP-hypersensitive patients clinical peach but not apple. Patients and methods: Based on observation who experienced 7 apple-induced anaphylactic reactions that 6 cases followed ingestion fruit after fasting, open food challenges were carried out 12 tolerant Results: Four (33%) reacted oral challenge. Conclusion: Fasting seems play a relevant role expression LTP. It possible empty gastrointestinal tract allergen absorbed more rapidly. Alternatively, might digest matrix efficiently, thus increasing concentration purified comes contact gut mucosa.
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