Obesity and Type 2 Diabetes mellitus induce lipopolysaccharide tolerance in rat neutrophils.

作者: Wilson Mitsuo Tatagiba Kuwabara , Caroline Naomi Fukusawa Yokota , Rui Curi , Tatiana Carolina Alba-Loureiro

DOI: 10.1038/S41598-018-35809-2

关键词: ImmunityImmunologyTLR4Type 2 diabetesChemokineLipopolysaccharideInnate immune systemDiabetes mellitusType 2 Diabetes MellitusMedicine

摘要: … from obese and type 2 diabetic rats are tolerant to LPS. This tolerance may be the explanation for the higher rates of death in obese and diabetic individuals as a consequence of …

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