作者: Jitender Bhandal , Sarah E. Boston
DOI: 10.1111/J.1532-950X.2011.00811.X
关键词: Histopathology 、 Cytology 、 Amputation 、 Medicine 、 Osteosarcoma 、 Internal fixation 、 Surgery 、 Chemotherapy 、 Lameness 、 Pathologic fracture 、 General Veterinary
摘要: Objective: To evaluate clinical presentation of pathologic fractures associated with suspected or confirmed osteosarcoma in dogs and to assess treatment survival times. Study design: Case series. Animals: Dogs (n=25) appendicular fracture. Methods: Medical records (January 1997–May 2008) fracture a were reviewed. included if they had radiographic evidence presumptive definitive diagnosis osteosarcoma. Radiographic details, histopathology, and/or cytology findings recorded. Overall median time (MST) MST treated calculated. Age, sex, breed, other concurrent evaluated. Results: Rottweilers, Irish Wolfhounds, Greyhounds the most common breeds represented. Most minor trauma 60% lameness preceding fracture. commonly, nondisplaced minimal comminution. None pulmonary metastases at admission. Immediate (13 dogs; 52%) delayed (4; 16%) euthanasia performed. One dog was not died 90 days after diagnosis. Three (12%) by amputation alone, 1 (4%) chemotherapy, 3 internal fixation using an interlocking nail. day (range, 0–623 days) 406.5 days. Histologic confirmation available all 6 euthanatized dogs. Conclusions: Treatment should be considered as option owners desire options.