Global distribution of the sickle cell gene and geographical confirmation of the malaria hypothesis

作者: Frédéric B Piel , Anand P Patil , Rosalind E Howes , Oscar A Nyangiri , Peter W Gething

DOI: 10.1038/NCOMMS1104

关键词: Balancing selectionDemographyAllele frequencyBiologyGlobal distributionSickle haemoglobinTransmission intensityMalariaSickle cell geneHeterozygous carrier

摘要: … vivax 38 are also considered as likely to contribute to the unresolved geographical relationship in India. Ongoing work to create an open-access database for several malaria protective …

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