Duration of human chorionic gonadotropin surveillance for partial hydatidiform moles

作者: Isaac Lavie , Gautam G Rao , Diego H Castrillon , David S Miller , John O Schorge

DOI: 10.1016/J.AJOG.2004.12.080

关键词: Human chorionic gonadotropin levelIn patientGestational trophoblastic neoplasiaGynecologyMolar pregnancyChorionic gonadotrophinPartial Hydatidiform MoleMedicineOffice visitsHuman chorionic gonadotropinObstetrics

摘要: Objective Partial hydatidiform moles infrequently progress to gestational trophoblastic neoplasia. The purpose of this study was determine the optimal duration human chorionic gonadotropin surveillance. Study design We retrospectively reviewed clinical follow-up all women who were diagnosed with partial mole at our institution from 1983 2003. Results One hundred sixty-three patients identified a median age 23 years (range, 14-42 years). Seventy-four (45%) attained undetectable levels gonadotropin; none had Forty completed 6 months recommended follow-up; conceived during surveillance, and 28 did not return for any further office visits 1 5 after achieving remission. Eighty-three (51%) lost before normalization gonadotropin. Six (4%) stage I neoplasia Conclusion Our results support suggestion that single level evacuation is sufficient ensure remission in moles.

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