Single-neuron recordings from unanesthetized mouse dorsal cochlear nucleus

作者: Wei-Li Diana Ma , Stephan D. Brenowitz

DOI: 10.1152/JN.00427.2011

关键词: NeuroscienceGenetic modelNeuronGerbilFuture studiesAuditory PhysiologyCochlear nucleusBiologyDorsal cochlear nucleus

摘要: Because of the availability disease and genetic models, mouse has become a valuable species for auditory neuroscience that will facilitate long-term goals understanding neuronal mechanisms underlying perception processing sounds. The goal this study was to define basic sound-evoked response properties single neurons in dorsal cochlear nucleus (DCN). Neurons producing complex spikes were distinguished as cartwheel cells (CWCs), other classified according map scheme previously developed DCN. Similar observations rodent species, DCN exhibit relatively little sound-driven inhibition. As result, type III most commonly observed response. Our findings are generally consistent with model function been cat gerbil, suggesting vivo preparation be useful tool future studies physiology.

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