Fatty liver index is associated with the risk of testosterone deficiency in aging men without metabolic syndrome.

摘要: OBJECTIVES Non-alcoholic fatty liver disease (NAFLD) is suggested to be a precursor of metabolic syndrome (MetS) and could influence the risk testosterone deficiency (TD). Fatty index (FLI) simple useful screening tool for NAFLD. We determined association between NAFLD assessed by FLI TD in aging Taiwanese men, especially those without MetS. MATERIALS AND METHODS A free health program was conducted men (age: >40 years) medical center Kaohsiung, Taiwan. All participants underwent physical examination; answered questionnaire assessing demographics, history, clinical symptoms TD; provided 20-mL whole blood samples biochemical, adipocytokine, hormonal evaluations. The evaluated using FLI. presence ruled out if value <25 ≥35. RESULTS total 552 (mean age: 54.7 ± 7.7 years) were enrolled. prevalence rates MetS significantly higher among with than (both p < 0.001). correlated (TT) adipocytokines associated insulin resistance, such as adiponectin, leptin, retinol-binding protein-4 (RBP-4) levels, respectively (all Among MetS, at had 3.82 8.50 times TD, respectively, after adjusting potential covariates. CONCLUSION Our findings also suggest that resistance may an important link inter-relationships NAFLD, TD. Further population-based studies larger sample sizes different ethnicities are warranted confirm these preliminary results.