Functional systems with orthogonal dynamic covalent bonds.

摘要: This review summarizes the use of orthogonal dynamic covalent bonds to build functional systems. Dynamic are unique because their dual nature. They can be as labile non-covalent interactions or permanent bonds, depending on conditions. Examples from nature, reaching role disulfides in protein folding thioester exchange polyketide biosynthesis, indicate how best used Several synthetic systems that employ a single type have been reported. Considering most make simultaneous several types together, one would expect literature contain many examples which different similarly tandem. However, incorporation into is surprisingly rare and recent development. available material comprehensively, covering remarkably diverse collection functions. probably more revealing than specific functions addressed questions asked consistently quite unusual, very demanding highly original, focusing molecular self-sort, self-heal, adapt, exchange, replicate, transcribe, even walk “think” (logic gates). focus adventurous chemistry off beaten track supports promise with we ask otherwise cannot asked. The broad range concepts covered should appeal supramolecular organic chemist but also broader community.