Transscleral optical coherence tomography--an experimental study in ex-vivo human eyes.

摘要: Background and Objective To evaluate the potentials of a 1310-nm optical coherence tomography (OCT) system to penetrate highly backscattering sclera in enucleated human eyes provide visualization intraocular structures by transscleral imaging. Study Design/Materials Methods OCT-images were generated an experimental prototype (Medical Laser Center, Lubeck, Germany) using superluminescence diode with wavelength 1310 nm. OCT-images taken from two 100–200 axial scans 60 Hz line scan frequency compared subsequent histologic sections. Results Transscleral OCT allowed penetration anterior chamber angle could be completely identified. Some change within eye segment demonstrated high accuracy. Additionally, limited demonstration ciliary body region was achieved. Due signal intensity no detailed imaging pars plana plicata possible. However, more posterior measurements retinal detachment. Conclusions OCT lightsources longer than that used conventional provides promising technique at resolution allowing segment. Lasers Surg. Med. 30:209-215, 2002. © 2002 Wiley-Liss, Inc.