Microcircuit dynamics of map plasticity in barrel cortex

摘要: Functional reorganization of the whisker map in rodent barrel cortex has long served as a model for cortical plasticity following changes sensory experience. Given heterogeneity neuronal response properties neocortex, it remained unclear how individual neurons microcircuit are affected. Novel vivo imaging and electrophysiology methods allow longitudinal recording same neurons' functional therefore have critical ability to resolve direction dynamics change progresses. Tracking responsiveness before after trimming uncovered diverse effects neurons, suggesting that will be essential elucidating mechanisms within microcircuits.