Formalin dab, the effective way of treating haemorrhagic radiation proctitis: a randomized trial from a tertiary care hospital in South India

摘要: Aim  Chronic radiation proctitis with bleeding is a common problem encountered following radiotherapy for pelvic malignancy. Sucralfate-steroid enema and formalin dab are two nonsurgical treatments. A randomized trial was conducted to compare the efficacy of these methods. Method  This prospective controlled in Jawaharlal Institute Postgraduate Medical Education & Research (JIPMER) from August 2005 May 2007. One-hundred patients chronic proctitis, presenting as rectal after carcinoma cervix, were recruited randomly allocated into treatment groups: Group 1, dab; 2, sucralfate-steroid retention enema. The mean age 51.3 ± 5.1 years. interval between end onset 12.3  ± 3.5 months. Symptom score sigmoidoscopic grade assessed before, at 1 month after, treatment. Results  Ninety per cent 1 74.5% 2 responded (P = 0.038). In spite having higher median symptom before treatment, demonstrated marked decrease compared difference once again statistically significant (P = 0.000). Similarly, significantly lower There no specific treatment-related complications either group. Conclusions  Formalin (4%) superior haemorrhagic proctitis.