Cloning and sequencing of the gene encoding the AmpC β-lactamase of Morganella morganii
作者： Guilène Barnaud , Guillaume Arlet , Claude Danglot , Alain Philippon
DOI: 10.1111/J.1574-6968.1997.TB10260.X
关键词: Morganella morganii 、 Escherichia coli 、 Plasmid 、 Gene 、 Enterobacter cloacae 、 Microbiology 、 Genetics 、 Biology 、 Citrobacter freundii 、 Enterobacteriaceae 、 Nucleic acid sequence
摘要: The chromosomal β-lactamase gene of a clinical isolate Morganella morganii was cloned in Escherichia coli and sequenced. had pI 7.4 conferred typical AmpC susceptibility pattern. insert obtained found to encode protein 379 amino acids. Its deduced acid sequence revealed it be class C β-lactamase: 39–56% identity with β-lactamases Serratia marcescens, Yersinia enterocolitica, Citrobacter freundii, Enterobacter cloacae coli; 37–56% plasmid-mediated (MOX-1, CMY-1, FOX-1, ACT-1, LAT-1, BIL-1 CMY-2). ampC linked only part which (450 bp) homologous the regulatory ampR genes β-lactamases.
oup.com
sci-hub.se 参考文章(22)
M Galleni, F Lindberg, S Normark, S Cole, N Honore, B Joris, J M Frere, Sequence and comparative analysis of three Enterobacter cloacae ampC beta-lactamase genes and their products. Biochemical Journal. ,vol. 250, pp. 753- 760 ,(1988) , 10.1042/BJ2500753
N. Honoré, M.H. Nicolas, S.T. Cole, Inducible cephalosporinase production in clinical isolates of Enterobacter cloacae is controlled by a regulatory gene that has been deleted from Escherichia coli. The EMBO Journal. ,vol. 5, pp. 3709- 3714 ,(1986) , 10.1002/J.1460-2075.1986.TB04704.X
F Lindberg, S Normark, Common mechanism of ampC beta-lactamase induction in enterobacteria: regulation of the cloned Enterobacter cloacae P99 beta-lactamase gene. Journal of Bacteriology. ,vol. 169, pp. 758- 763 ,(1987) , 10.1128/JB.169.2.758-763.1987
Frederik LINDBERG, Staffan NORMARK, Sequence of the Citrobacter freundii OS60 chromosomal ampCβ‐lactamase gene FEBS Journal. ,vol. 156, pp. 441- 445 ,(1986) , 10.1111/J.1432-1033.1986.TB09601.X
B. Jaurin, T. Grundstrom, ampC cephalosporinase of Escherichia coli K-12 has a different evolutionary origin from that of beta-lactamases of the penicillinase type Proceedings of the National Academy of Sciences of the United States of America. ,vol. 78, pp. 4897- 4901 ,(1981) , 10.1073/PNAS.78.8.4897
M. MATTHEW, A. M. HARRIS, M. J. MARSHALL, G. W. ROSS, The use of analytical isoelectric focusing for detection and identification of beta-lactamases. Microbiology. ,vol. 88, pp. 169- 178 ,(1975) , 10.1099/00221287-88-1-169
F. Grimont, P.A.D. Grimont, Ribosomal ribonucleic acid gene restriction patterns as potential taxonomic tools Annales de l'Institut Pasteur / Microbiologie. ,vol. 137, pp. 165- 175 ,(1986) , 10.1016/S0769-2609(86)80105-3
Brian G. Spratt, Philip J. Hedge, Stephan te Heesen, Alex Edelman, Jenny K. Broome-Smith, Kanamycin-resistant vectors that are analogues of plasmids pUC8, pUC9, pEMBL8 and pEMBL9 Gene. ,vol. 41, pp. 337- 342 ,(1986) , 10.1016/0378-1119(86)90117-4
A. Philippon, G. Arlet, P. H. Lagrange, Origin and impact of plasmid-mediated extended-spectrum beta-lactamases European Journal of Clinical Microbiology & Infectious Diseases. ,vol. 13, ,(1994) , 10.1007/BF02390681
Kazuhide Nomura, Tadashi Yoshida, Nucleotide sequence of the Serratia marcescens SR50 chromosomal ampC β-lactamase gene Fems Microbiology Letters. ,vol. 70, pp. 295- 299 ,(1990) , 10.1111/J.1574-6968.1990.TB13992.X