Insulin receptor signaling. Activation of multiple serine kinases.

作者: M P Czech , J K Klarlund , K A Yagaloff , A P Bradford , R E Lewis

DOI: 10.1016/S0021-9258(18)37908-0

关键词: Insulin receptorSerineKinaseMolecular biologyEnzymeBiochemistryChemistryPhosphorylationInsulinSerine/threonine-specific protein kinase

摘要: Le role de l'insuline dans la cellule normale est discute. Au fait l'insuline, en se fixant sur son recepteur, induit dephosphorylation certaines enzymes pour les activer ou inhiber. D'autre part, elle phosphorylation d'autres proteines sans influencer leurs activites. Differentes cibles sont discutees ainsi que substrats potentiels. Deux mecanismes hypothetiques phosphorylation, mediee par discutes

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