Stroke patterns, etiology, and prognosis in patients with diabetes mellitus

作者: Th. Karapanayiotides , B. Piechowski-Jozwiak , G. van Melle , J. Bogousslavsky , G. Devuyst

DOI: 10.1212/01.WNL.0000123252.55688.05

关键词: Vascular diseaseInternal medicineIntracerebral hemorrhageSurgeryEtiologyRisk factorOdds ratioCohortMedicineDiabetes mellitusStroke

摘要: Background: Although diabetes mellitus (DM) is a risk factor for stroke, it unclear whether stroke features are different in diabetic vs nondiabetic individuals. Objective: To assess the role of DM patients. Methods: Risk factors, etiology, lesion topography, clinical features, and outcome were assessed 611 individuals (history or fasting plasma glucose level ≥7.0 mmol/L) among 4,064 consecutive patients Lausanne Stroke Registry. Results: Patients with 5.3 years older than non-DM After multivariate analysis, was associated lower relative prevalence intracerebral hemorrhage (ICH; odds ratio [95% CI]: 0.63 (0.45 to 0.9); p = 0.022), higher subcortical infarction (SCI; 1.34 [1.11 1.62]; 0.009), frequency small-vessel (SVD; 1.78 [1.31 3.82]; 0.012) large-artery (LAD; 2.02 2.02]; 0.002) disease. In cohort patients, there no interaction either hypertension age outcomes ICH, SCI, SVD, LAD. Moderate severe deficit on admission (31.1 31.6%; 0.4) poor functional at 1 month (14.1 15.3%; 0.24) did not differ compared neither (0.86 [0.63 1.11]; 0.15) nor (1.09 [0.91 1.39]; 0.32) outcome. Conclusions: Diabetic specific patterns type, topography but There between age.

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