Modern concepts in the biology, diagnosis, differential diagnosis and treatment of primary central nervous system lymphoma
作者： M Deckert , A Engert , W Brück , A J M Ferreri , J Finke
DOI: 10.1038/LEU.2011.169
关键词: Differential diagnosis 、 Pathology 、 Molecular pathogenesis 、 Primary CNS Lymphoma 、 Radiation therapy 、 Lymphoma 、 Internal medicine 、 Diffuse large B-cell lymphoma 、 Medicine 、 Oncology 、 Primary central nervous system lymphoma
摘要: Recent studies addressing the molecular characteristics of PCNSL, which is defined as malignant B-cell lymphoma with morphological features DLBCL, have significantly improved our understanding pathogenesis this entity, associated an inferior prognosis compared DLBCL outside CNS. This unfavorable stimulated intense efforts to improve therapy and induced recent series clinical studies, addressed role radiotherapy various chemotherapeutic regimens. review combines discussion diagnosis, differential diagnosis progress in well therapeutic options PCNSL.
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