Pseudolaric acid B triggers ferroptosis in glioma cells via activation of Nox4 and inhibition of xCT.
作者： Zongqi Wang , Ye Ding , Xuanzhong Wang , Shan Lu , Chongcheng Wang
DOI: 10.1016/J.CANLET.2018.04.021
关键词: Deferoxamine 、 Chemistry 、 Downregulation and upregulation 、 Glutathione 、 Transferrin receptor 、 Lipid peroxidation 、 Programmed cell death 、 Intracellular 、 Cell biology 、 Mitochondrion
摘要: … To test whether PAB induced ferroptosis in glioma cells, we assayed PAB-induced changes in intracellular ferrous … of ferrous iron in the removed glioma tissue was assayed. We found …
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