作者: J. D. Cameron , S. T. Hagen , R. R. Waterfield , L. T. Furcht
DOI: 10.3109/02713688809047035
关键词: Cell biology 、 Integrin 、 Biochemistry 、 Type IV collagen 、 Cell adhesion molecule 、 Biology 、 Basement membrane 、 Cell adhesion 、 Laminin 、 Fibronectin 、 Extracellular matrix
摘要: Extracellular matrix and basement membrane proteins are important in promoting the adhesion migration of various cell types. Laminin type IV collagen found membranes throughout body while fibronectin is associated with some basal lamina, loose connective tissue, all fluids. In current study fibronectin, laminin, were assessed to determine their effect on dissociated rabbit epithelial cells. a kinetic analysis was be most effective three adhesion. Cell promoted by could modulated an arg-gly-asp-ser (RGDS) peptide, sequence which within molecule. dose-response experiments effectively at concentrations as low 4×10–16 moles per well 96 tissue culture plates. Type protein tested chemotactic and...