Comparison of Percutaneous Mitral Valve Repair Versus Conservative Treatment in Severe Functional Mitral Regurgitation.

摘要: Percutaneous mitral valve repair (PMVR) using the MitraClip System is feasible and entails clinical improvement even in patients with high surgical risk severe functional regurgitation (MR). The aim of this study was to assess survival rates outcome severe, MR treated optimal medical therapy (OMT) compared those who received device. Sixty OMT were a propensity-matched cohort 60 underwent PMVR. Baseline demographics echocardiographic variables similar between 2 groups. mean age 75 years, 67% men. median logistic EuroSCORE II 17% 6%, respectively, because presence several co-morbidities. mechanism all cases an ischemic etiology 52% patients. Median left ventricle ejection fraction 34%. All symptomatic for dyspnea 63% 12% New York Heart Association class III IV, respectively. In PMVR group, procedure associated safety very low incidence procedural complications no occurrence inhospital mortality. After follow-up 515 days (248 828 days), demonstrated overall survival, freedom from cardiac death free readmission due disease curves higher than conservatively (log-rank test p = 0.007, 0.002, 0.04, respectively). conclusion, offers valid option selected better outcomes OMT.