Paraneoplastic Hypercalcemia in a Dog with Benign Renal Angiomyxoma

作者: Isuru Gajanayake , Simon L. Priestnall , Livia Benigni , Kate English , Brian A. Summers

DOI: 10.1177/104063871002200523

关键词: PolyuriaVimentinPathologyKidneyHistopathologyAbdominal ultrasonographyHypercalcaemiaImmunostainingAngiomyxomaMedicine

摘要: An 11-year-old, male, neutered crossbred Collie dog was presented for a history of polydipsia and polyuria. Diagnostic investigations revealed total ionized hypercalcemia an increased concentration parathyroid hormone–related peptide. Abdominal ultrasonography contrast-enhanced computed tomography the abdomen right-sided, cystic-appearing renal mass. Cytological examination ultrasound-guided aspirates mass high numbers spindle cells. The removed en bloc via ureteronephrectomy. Histopathological neoplastic cells in loosely packed interlacing streams within myxomatous stroma. Immunohistochemical with vimentin, von Willebrand Factor, α-smooth muscle actin confirmed to be angiomyxoma. A minority showed positive cytoplasmic peptide immunostaining. resolved following surgery, parathyroi...

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