Splenic angiomyxoma with intravascular tumor embolus in a dog: a case report
作者： Eun-Mi LEE , Ah-Young KIM , Eun-Joo LEE , Jin-Kyu PARK , Tae-Hwan KIM
DOI: 10.1292/JVMS.15-0715
关键词: Angiomyxoma 、 Splenic Neoplasm 、 Hepatic stellate cell 、 Spleen 、 Parenchyma 、 Pathology 、 Myxoma 、 Desmin 、 Anatomy 、 Immunohistochemistry 、 Medicine
摘要: A 13-year-old castrated male Yorkshire terrier dog had a soft splenic mass, which measured 11 cm in the greatest diameter. Microscopically, parenchyma of spleen was completely replaced by myxoid substances. Numerous spindle and stellate cells were loosely arranged stroma, variable vessels sizes observed loose matrix with poorly defined margins. Immunohistochemical analysis showed that tumor positive for desmin alpha-SMA, but negative S-100. Interestingly, intravascular embolus α-SMA expression observed. This case is meaningful, because angiomyxoma, rare dogs, occurs spleen. Even human cases, angiomyxoma not reported.
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