An attempt for fast separation of enantiomers in nano-liquid chromatography and capillary electrochromatography.
作者： Giovanni D'Orazio , Rusudan Kakava , Alessandro Volonterio , Salvatore Fanali , Bezhan Chankvetadze
关键词: Enantiomer 、 Capillary action 、 Analyte 、 Chromatography 、 Capillary electrochromatography 、 Analytical chemistry 、 Materials science 、 Nano liquid chromatography
摘要: In the present study, an attempt was made to achieve separation of enantiomers within a minute in nano-LC and CEC. order this goal several parameters were optimized from viewpoint property chiral analytes, concentration selector packing material, capillary dimensions, mode. The applied sulfoxides could be resolved with analysis time <1 min. Some instrumental obstacles hindering further reduction are also highlighted.
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cheric.org参考文章(19)
Bezhan Chankvetadze, Enantioseparations by high-performance liquid chromatography using polysaccharide-based chiral stationary phases: an overview. Methods of Molecular Biology. ,vol. 970, pp. 81- 111 ,(2013) , 10.1007/978-1-62703-263-6_5
Stefanie Abel, Markus Juza, Less Common Applications of Enantioselective HPLC Using the SMB Technology in the Pharmaceutical Industry Chiral Separation Techniques: A Practical Approach, Third Edition. pp. 203- 273 ,(2007) , 10.1002/9783527611737.CH7
Bezhan Chankvetadze, Chiyo Yamamoto, Yoshio Okamoto, Extremely High Enantiomer Recognition in HPLC Separation of Racemic 2-(Benzylsulfinyl)benzamide Using Cellulose Tris(3,5-dichlorophenylcarbamate) as a Chiral Stationary Phase Chemistry Letters. ,vol. 29, pp. 1176- 1177 ,(2000) , 10.1246/CL.2000.1176
Bezhan Chankvetadze, Eiji Yashima, Yoshio Okamoto, Chloromethylphenylcarbamate derivatives of cellulose as chiral stationary phases for high-performance liquid chromatography Journal of Chromatography A. ,vol. 670, pp. 39- 49 ,(1994) , 10.1016/0021-9673(94)80278-5
Salvatore Fanali, Giovanni D’Orazio, Tivadar Farkas, Bezhan Chankvetadze, Comparative performance of capillary columns made with totally porous and core–shell particles coated with a polysaccharide-based chiral selector in nano-liquid chromatography and capillary electrochromatography Journal of Chromatography A. ,vol. 1269, pp. 136- 142 ,(2012) , 10.1016/J.CHROMA.2012.06.021
Bezhan Chankvetadze, Recent developments on polysaccharide-based chiral stationary phases for liquid-phase separation of enantiomers. Journal of Chromatography A. ,vol. 1269, pp. 26- 51 ,(2012) , 10.1016/J.CHROMA.2012.10.033
Giovanni D’Orazio, Salvatore Fanali, Pressurized nano-liquid–junction interface for coupling capillary electrochromatography and nano-liquid chromatography with mass spectrometry Journal of Chromatography A. ,vol. 1317, pp. 67- 76 ,(2013) , 10.1016/J.CHROMA.2013.08.052
Bezhan Chankvetadze, Chiyo Yamamoto, Yoshio Okamoto, Very Fast Enantioseparation in High-performance Liquid Chromatography Using Cellulose Tris(3,5-dimethylphenylcarbamate) Coated on Monolithic Silica Support Chemistry Letters. ,vol. 32, pp. 850- 851 ,(2003) , 10.1246/CL.2003.850
Johannes P.C. Vissers, Henk A. Claessens, Carel A. Cramers, Microcolumn liquid chromatography: Instrumentation, detection and applications Journal of Chromatography A. ,vol. 779, pp. 1- 28 ,(1997) , 10.1016/S0021-9673(97)00422-6
Jun Shen, Yoshio Okamoto, Efficient Separation of Enantiomers Using Stereoregular Chiral Polymers Chemical Reviews. ,vol. 116, pp. 1094- 1138 ,(2016) , 10.1021/ACS.CHEMREV.5B00317