Hepatocyte migration during liver development requires Prox1
作者： Beatriz Sosa-Pineda , Jeffrey T. Wigle , Guillermo Oliver
DOI: 10.1038/76996
关键词: Biology 、 Cell biology 、 Cell growth 、 Hepatocyte 、 Septum transversum 、 Population 、 Cellular differentiation 、 Embryogenesis 、 Cadherin 、 Immunology 、 Cell adhesion molecule
摘要: Several genes are required during the early phases of liver specification, proliferation and differentiation1,2,3. Here we report that Prox1 is for hepatocyte migration. Loss leads to formation a smaller with reduced population clustered hepatocytes surrounded by laminin-rich basal membrane.
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