Combining surface topography with polymer chemistry: Exploring new interfacial biological phenomena

摘要: The review focuses on the combination of surface topography and chemical modification with grafting polymer chains to develop optimal material interfaces for biological biomedical applications. Understanding how chemistry correlate interfacial properties functions a is important development biomaterials. Synergies between these two are known exist, but have not been exploited extensively biomaterial design. Preliminary studies suggest that may only enhance properties, also give opposite those corresponding smooth surface, even other unexpected properties. This summarizes some recent in this area, mostly carried out our own laboratory, as examples illustrate synergistic be obtained by combining chemistry. It hoped will stimulate more thorough exploration topography–chemistry synergy means injecting “new life” into efforts novel bio-functional surfaces.