Fascicular nerve allograft evaluation. Part 1: comparison with autografts by light microscopy.

作者: Robert Levinthal , W. Jann Brown , Robert W. Rand

DOI: 10.3171/JNS.1978.48.3.0423

关键词: Nerve fascicleMedicineNerve allograftAnatomyAntigenicityMacrophageTissue typingPathologyTransplantation

摘要: ✓ In a comparative experiment, transplantation of orthotopic nerve fascicle was performed on 100 sciatic nerves between inbred, antigenically identified rats. The authors studied cellular response, macrophage reaction, connective-tissue myelination, and distal/proximal axonal ratios, but no difference could be established allografted autografted fascicles after 2 months. Moreover, there evidence any graded rejection phenomenon dependent differences tissue typing. Theories for the decreased antigenic reaction are proposed.

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