作者: Torsten Roed , Anne-Mette Lebech , Andreas Kjaer , Nina Weis
DOI: 10.1111/J.1475-097X.2012.01152.X
关键词: Chlamydia 、 Internal medicine 、 Hepatitis C virus 、 Medicine 、 Confounding 、 Protective factor 、 Meta-analysis 、 Coronary artery disease 、 Viral hepatitis 、 Observational study 、 Virology
摘要: SummaryBackground Several chronic infections have been associated with cardiovascular diseases, including Chlamydia pneumoniae, human immunodeficiency virus and viral hepatitis. This review evaluates the literature on association between hepatitis C (HCV) infection risk of coronary artery disease (CAD). Methods Studies were identified using several databases. Only studies CAD in patients HCV included. A set criteria for evaluating potential biases was made, based known confounders observational research. Data not synthesized because large heterogeneity included studies. Results Twelve eligible references identified. Nine did comply our minimizing bias, six evaluated as potentially heavily biased. The highest quality showed a trend towards CAD. Five this (three significantly), while one that protective factor against CAD. Conclusion Our findings suggest an increased HCV-infected individuals. Further are needed to confirm evaluate magnitude association. Clinicians should be aware strive reduce factors infection.