Hepatitis C virus infection and risk of coronary artery disease: a systematic review of the literature.

作者: Torsten Roed , Anne-Mette Lebech , Andreas Kjaer , Nina Weis

DOI: 10.1111/J.1475-097X.2012.01152.X

关键词: ChlamydiaInternal medicineHepatitis C virusMedicineConfoundingProtective factorMeta-analysisCoronary artery diseaseViral hepatitisObservational studyVirology

摘要: SummaryBackground Several chronic infections have been associated with cardiovascular diseases, including Chlamydia pneumoniae, human immunodeficiency virus and viral hepatitis. This review evaluates the literature on association between hepatitis C (HCV) infection risk of coronary artery disease (CAD). Methods Studies were identified using several databases. Only studies CAD in patients HCV included. A set criteria for evaluating potential biases was made, based known confounders observational research. Data not synthesized because large heterogeneity included studies. Results Twelve eligible references identified. Nine did comply our minimizing bias, six evaluated as potentially heavily biased. The highest quality showed a trend towards CAD. Five this (three significantly), while one that protective factor against CAD. Conclusion Our findings suggest an increased HCV-infected individuals. Further are needed to confirm evaluate magnitude association. Clinicians should be aware strive reduce factors infection.

参考文章(50)
Nasir Khokhar, Saima A Niazi, Chronic liver disease related mortality pattern in Northern Pakistan. Jcpsp-journal of The College of Physicians and Surgeons Pakistan. ,vol. 13, pp. 495- 497 ,(2003)
Crişan D, Radu C, Rusu M, Serban A, Neculoiu D, Grigorescu M, Acalovschi M, Grigorescu, Metabolic syndrome, insulin resistance and adiponectin level in patients with chronic hepatitis C. Journal of Gastrointestinal and Liver Diseases. ,vol. 17, pp. 147- ,(2008)
J. R. KRAMER, J. A. DAVILA, E. D. MILLER, P. RICHARDSON, T. P. GIORDANO, H. B. EL-SERAG, The validity of viral hepatitis and chronic liver disease diagnoses in Veterans Affairs administrative databases Alimentary Pharmacology & Therapeutics. ,vol. 27, pp. 274- 282 ,(2007) , 10.1111/J.1365-2036.2007.03572.X
Ignatius W. Fong, Emerging relations between infectious diseases and coronary artery disease and atherosclerosis Canadian Medical Association Journal. ,vol. 163, pp. 49- 56 ,(2000)
Helen E Harris, ME Ramsay, NJ Andrews, None, Survival of a national cohort of hepatitis C virus infected patients, 16 years after exposure Epidemiology and Infection. ,vol. 134, pp. 472- 477 ,(2006) , 10.1017/S0950268805005340
Chia-Chi Wang, Jia-Horng Kao, Hepatitis C virus infection, lipids, and coronary heart disease: a Pandora's box. Hepatology. ,vol. 51, pp. 343- 343 ,(2010) , 10.1002/HEP.23393
Magda Shaheen, Diana Echeverry, Marcela Garcia Oblad, Marie I. Montoya, Senait Teklehaimanot, Abbasi J. Akhtar, Hepatitis C, metabolic syndrome, and inflammatory markers: results from the Third National Health and Nutrition Examination Survey [NHANES III]. Diabetes Research and Clinical Practice. ,vol. 75, pp. 320- 326 ,(2007) , 10.1016/J.DIABRES.2006.07.008
M. Garau, H.F. Zhang, D. Mills, S. Wagner, D. Freedman, R. Termini, T.N.32 HCV INFECTION IS ASSOCIATED WITH HIGH COMORBIDITY BURDEN IN EUROPE Digestive and Liver Disease. ,vol. 42, ,(2010) , 10.1016/S1590-8658(10)60437-9
WILLIAM D. CAREY, JOHN A. DUMOT, RONNIE R. PIMENTEL, DAVID S. BARNES, ROBERT E. HOBBS, J. MICHAEL HENDERSON, DAVID P. VOGT, JAMES T. MAYES, MARY KAY WESTVEER, KIRK A. EASLEY, The prevalence of coronary artery disease in liver transplant candidates over age 50. Transplantation. ,vol. 59, pp. 859- 864 ,(1995) , 10.1097/00007890-199503000-00010
Janaki Amin, Matthew G Law, Gregory Dore, Mortality in patients with hepatitis B or hepatitis C: authors' reply The Lancet. ,vol. 368, pp. 1767- 1767 ,(2006) , 10.1016/S0140-6736(06)69729-8