Turnover of bacterial cell wall peptidoglycans.

摘要: Abstract The cell wall peptidoglycan of Lactobacillus acidophilus strain 63 AM Gasser has been shown to turn over rapidly during balanced exponential growth and recovery from amino acid deprivation. In contrast, turnover either pulse-labeled or extensively labeled Streptococcus faecalis ATCC 9790 was not detected by the same method experimental conditions. S. faecalis, could be induced brief exposure cells a low concentration lysozyme in presence penicillin. rate growing cultures L. equivalent loss about one third their per generation. This due cellular lysis since protein below detectable levels. Comparably rapid rates generation were observed slowly (30% lost generation) mutant which autolyzed at fifth wild type (25% generation). for 6 more generations, preceded lag 0.8 2 times. Turnover pulses less than 0.2 generations periods exceeding generations. These last two results cannot interpreted as indicating that newly made is immune both cases nonsynchronized used, short would eventually age culture grew. addition chloramphenicol deprivation valine completely prevented turnover. absence (and other species) suggests an essential feature growth. On hand, acidophilus, appears closely associated with portion synthesis related surface) enlargement thickening.