Effect of Notch expression in glioma stem cells on therapeutic response to chemo-radiotherapy in recurrent glioblastoma.

作者: Norihiko Saito , Kazuya Aoki , Nozomi Hirai , Satoshi Fujita , Junya Iwama

DOI: 10.1007/S10014-015-0215-7

关键词: Notch signaling pathwayBevacizumabStem cellChemotherapyInternal medicineRadiation therapyOncologyCellular differentiationBiologyHES1PathologyGlioma

摘要: … VEGF-positive glioma cells were higher in recurrent glioblastoma after radiotherapy and chemotherapy. To determine the clinical importance of Notch-1 expression in glioblastoma, we …

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