Minicircle DNA Vectors Devoid of Bacterial DNA Result in Persistent and High-Level Transgene Expression in Vivo
作者： Zhi-Ying Chen , Cheng-Yi He , Anja Ehrhardt , Mark A Kay
DOI: 10.1016/S1525-0016(03)00168-0
关键词: Plasmid 、 Blot 、 Transfection 、 Minicircle 、 Molecular biology 、 Gene silencing 、 Transgene 、 Expression cassette 、 In vivo 、 Biology
摘要: The loss of transgene expression has been a major obstacle to the development of nonviral vectors for the treatment of human diseases. We previously demonstrated that bacterial DNA …
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