Emergence of non-albicans Candida species in neonatal candidemia.

摘要: Background: Candida species are one of the most common causes blood stream infections among neonates and account for 9-13% such infections. Although albicans remains fungal isolate from neonatal candidemia, longitudinal studies have detected a shift towards non-albicans (NAC) species. Aim: To examine prevalence epidemiology candidemia infants admitted to our hospital. Materials Methods: Blood samples were collected 548 only those which yielded pure growth spp. included in study. The isolates identified as per standard mycological techniques antifungal susceptibility (AFS) was done by disc diffusion method. Results: Of total 132 study, NAC responsible 80.30% cases with C. parapsilosis (25.0%) tropicalis (21.97%) predominant species; whereas 19.70% caused albicans. AFS results revealed that 65.91, 73.49, 96.21% sensitive fluconazole (FLK), itraconazole (ITR), amphotericin B (AMB), respectively. Conclusion: Candidemia is an ominous prognostic sign important entity Strict infection control strategies, appropriate preventive therapeutic measures prophylactic use restrictive policy antibiotic should be implemented.