Peptide binding consensus of the NHE-RF-PDZ1 domain matches the C-terminal sequence of cystic fibrosis transmembrane conductance regulator (CFTR)

作者: Shusheng Wang , Ronald W Raab , Peter J Schatz , William B Guggino , Min Li

DOI: 10.1016/S0014-5793(98)00402-5

关键词: Consensus sequencePeptide bindingCystic fibrosis transmembrane conductance regulatorProtein structureSequence alignmentBiochemistryChemistryPeptide sequencePhosphoproteinPDZ domainCell biology

摘要: … NHE-RF contains two distinct protein interaction PDZ domains: NHE-RF-PDZ1 and NHE-RF-… sequences that interact with the NHE-RF PDZ domains and found that NHE-RF-PDZ1 is …

参考文章(17)
E J Weinman, D Steplock, Y Wang, S Shenolikar, Characterization of a protein cofactor that mediates protein kinase A regulation of the renal brush border membrane Na(+)-H+ exchanger. Journal of Clinical Investigation. ,vol. 95, pp. 2143- 2149 ,(1995) , 10.1172/JCI117903
T. Hug, T. Koslowsky, D. Ecke, R. Greger, K. Kunzelmann, Actin-dependent activation of ion conductances in bronchial epithelial cells. Pflügers Archiv: European Journal of Physiology. ,vol. 429, pp. 682- 690 ,(1994) , 10.1007/BF00373989
Ming Li, John D. McCann, Carole M. Liedtket, Angus C. Nairn, Paul Greengard, Michael J. Welsh, Cyclic AMP-dependent protein kinase opens chloride channels in normal but not cystic fibrosis airway epithelium Nature. ,vol. 331, pp. 358- 360 ,(1988) , 10.1038/331358A0
Nicole L. Stricker, Karen S. Christopherson, Byungdoo A. Yi, Peter J. Schatz, Ronald W. Raab, Glenn Dawes, Douglas E. Bassett, David S. Bredt, Min Li, PDZ domain of neuronal nitric oxide synthase recognizes novel C-terminal peptide sequences Nature Biotechnology. ,vol. 15, pp. 336- 342 ,(1997) , 10.1038/NBT0497-336
David Reczek, Mark Berryman, Anthony Bretscher, Identification of EBP50: A PDZ-containing Phosphoprotein that Associates with Members of the Ezrin-Radixin-Moesin Family Journal of Cell Biology. ,vol. 139, pp. 169- 179 ,(1997) , 10.1083/JCB.139.1.169
Patricia Hutchings, Hugh Rosen, Lorraine O'Reilly, Elizabeth Simpson, Siamon Gordon, Anne Cooke, Transfer of diabetes in mice prevented by blockade of adhesion-promoting receptor on macrophages. Nature. ,vol. 348, pp. 639- 642 ,(1990) , 10.1038/348639A0
C. H. C. Yun, S. Oh, M. Zizak, D. Steplock, S. Tsao, C.-M. Tse, E. J. Weinman, M. Donowitz, cAMP-mediated inhibition of the epithelial brush border Na+/H+ exchanger, NHE3, requires an associated regulatory protein. Proceedings of the National Academy of Sciences of the United States of America. ,vol. 94, pp. 3010- 3015 ,(1997) , 10.1073/PNAS.94.7.3010