Idiopathic chronic pancreatitis with periductal lymphoplasmacytic infiltration: clinicopathologic features of 35 cases

摘要: To clarify clinicopathologic features of idiopathic chronic pancreatitis with lymphoplasmacytic infiltration, we carried out a study 35 cases. There were two histologic groups, which have designated sclerosing and duct-centric pancreatitis. Lymphoplasmacytic (22 cases) was fibrosing process diffuse infiltrates involving pancreatic lobules ducts, adipose tissue, blood vessels, common bile duct. Obliterative phlebitis found in every case except for one. The similar to other fibrosclerosing disorders, one patient also had retroperitoneal fibrosis. Affected patients tended be elderly men. Idiopathic (13 characterized by inflammatory (including neutrophils) that denser the than interlobular fibrotic areas. Neutrophils prominent destruction duct epithelium commonly seen. Patient ages more broadly distributed Two bowel disease. We conclude sometimes called autoimmune pancreatitis, consists at least different processes. One these, is histologically unique lesion could manifestation disorders.