Isolation from and x-ray crystal structure of alexine, (1r,2r,3r,7s,8s)-3-hydroxymethyl-1,2,7-trihydroxypyrrolizidine [(2r,3r,4r,5s,6s)-2-hydroxymethyl-1-azabicyclo[3.3.0]octan-3,4,6-triol], a unique pyrrolizidine alkaloid

作者: R.J Nash , L.E Fellows , J.V Dring , G.W.J Fleet , A.E Derome

DOI: 10.1016/S0040-4039(00)87914-9

关键词: Pyrrolizidine alkaloidTriolStereochemistryHydroxymethylCrystal structureChemistryAlkaloid

摘要: … and identification of (lR,2R,3R,7S,8S)-3-hydroxymethyl-l,2,7-trihydroxypyrrolizidine … with a carbon substituent at C-1,' such as dihydroxyheliotridane (2),2 (1) is the first example of a …

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