Triclosan and silver compound containing medical devices

作者: Lester Sampath , Shanta Modak

DOI:

关键词: MicrobiologyMaterials scienceChlorhexidineTriclosanAntimicrobialCombinatorial chemistry

摘要: The present invention relates to polymeric medical articles comprising combinations of triclosan and silver-containing compounds. It is based, at least in part, on the discovery that these agents act synergistically, thereby permitting use relatively low levels both agents. While it had been previously found can be particularly useful when used conjunction with chlorhexidine, has further discovered having suitable antimicrobial properties may prepared, according invention, which contain without chlorhexidine. Such offer advantage preventing or inhibiting infection while avoiding undesirable adverse reactions chlorhexidine by individuals have sensitivity

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