Developing a Highly Stable PLGA-mPEG Nanoparticle Loaded with Cisplatin for Chemotherapy of Ovarian Cancer
作者： Lihua Cheng , Chengmeng Jin , Wen Lv , Qiuping Ding , Xu Han
DOI: 10.1371/JOURNAL.PONE.0025433
关键词: Drug formulations 、 Anticancer drug 、 Drug carrier 、 PLGA 、 Chemotherapy 、 Pharmacology 、 Ovarian cancer 、 Nanoparticle 、 Cisplatin 、 Chemistry
摘要: Background Cisplatin is a potent anticancer drug, but its clinical application has been limited due to undesirable physicochemical characteristics and severe side effects. Better drug formulations for cisplatin are highly desired.
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