Epigenetic modifications and human disease
作者： Anna Portela , Manel Esteller
DOI: 10.1038/NBT.1685
关键词: Nucleosome 、 Epigenetics 、 DNA methylation 、 Epigenomics 、 CpG site 、 Non-coding RNA 、 Biology 、 Genetics 、 Functional genomics 、 Histone 、 Computational biology
摘要: … develop when the wrong type of epigenetic marks are introduced or are added at the … epigenetic research and its role in disease, preparing ourselves for the surprises that epigenetics …
nature.com
sci-hub.se 
researchgate.net 参考文章(175)
Déborah Bourc'his, Guo-Liang Xu, Chyuan-Sheng Lin, Brooke Bollman, Timothy H Bestor, Dnmt3L and the Establishment of Maternal Genomic Imprints Science. ,vol. 294, pp. 2536- 2539 ,(2001) , 10.1126/SCIENCE.1065848
A. S. Chi, B. E. Bernstein, Developmental biology. Pluripotent chromatin state. Science. ,vol. 323, pp. 220- 221 ,(2009) , 10.1126/SCIENCE.1166261
Charles W. M. Roberts, Stuart H. Orkin, The SWI/SNF complex--chromatin and cancer. Nature Reviews Cancer. ,vol. 4, pp. 133- 142 ,(2004) , 10.1038/NRC1273
Akio Kuroda, Tibor A. Rauch, Ivan Todorov, Hsun Teresa Ku, Ismail H. Al-Abdullah, Fouad Kandeel, Yoko Mullen, Gerd P. Pfeifer, Kevin Ferreri, Insulin gene expression is regulated by DNA methylation. PLOS ONE. ,vol. 4, ,(2009) , 10.1371/JOURNAL.PONE.0006953
J. Espada, E. Ballestar, R. Santoro, M. F. Fraga, A. Villar-Garea, A. Nemeth, L. Lopez-Serra, S. Ropero, A. Aranda, H. Orozco, V. Moreno, A. Juarranz, J. C. Stockert, G. Langst, I. Grummt, W. Bickmore, M. Esteller, Epigenetic disruption of ribosomal RNA genes and nucleolar architecture in DNA methyltransferase 1 (Dnmt1) deficient cells Nucleic Acids Research. ,vol. 35, pp. 2191- 2198 ,(2007) , 10.1093/NAR/GKM118
S R Naidu, I M Love, A N Imbalzano, S R Grossman, E J Androphy, The SWI/SNF chromatin remodeling subunit BRG1 is a critical regulator of p53 necessary for proliferation of malignant cells Oncogene. ,vol. 28, pp. 2492- 2501 ,(2009) , 10.1038/ONC.2009.121
Heike C. Pieper, Bernd O. Evert, Oliver Kaut, Peter F. Riederer, Andreas Waha, Ullrich Wüllner, Different methylation of the TNF-alpha promoter in cortex and substantia nigra: Implications for selective neuronal vulnerability Neurobiology of Disease. ,vol. 32, pp. 521- 527 ,(2008) , 10.1016/J.NBD.2008.09.010
Alexander Meissner, Epigenetic modifications in pluripotent and differentiated cells Nature Biotechnology. ,vol. 28, pp. 1079- 1088 ,(2010) , 10.1038/NBT.1684
Marcus Bettstetter, Matthias Woenckhaus, Peter J Wild, Petra Rümmele, Hagen Blaszyk, Arndt Hartmann, Ferdinand Hofstädter, Wolfgang Dietmaier, Elevated nuclear maspin expression is associated with microsatellite instability and high tumour grade in colorectal cancer The Journal of Pathology. ,vol. 205, pp. 606- 614 ,(2005) , 10.1002/PATH.1732
Shima Nakanishi, Jung Shin Lee, Kathryn E. Gardner, Jennifer M. Gardner, Yoh-hei Takahashi, Mahesh B. Chandrasekharan, Zu-Wen Sun, Mary Ann Osley, Brian D. Strahl, Sue L. Jaspersen, Ali Shilatifard, Histone H2BK123 monoubiquitination is the critical determinant for H3K4 and H3K79 trimethylation by COMPASS and Dot1 Journal of Cell Biology. ,vol. 186, pp. 371- 377 ,(2009) , 10.1083/JCB.200906005