Napht- 2 -ylacetic acid derivatives to treat aids
作者： Paul Hrvatin , Randall W. Vivian , Elizabeth Bacon , Lianhong Xu , John O. Link
DOI:
关键词: Human immunodeficiency virus (HIV) 、 Organic chemistry 、 Acquired immunodeficiency syndrome (AIDS) 、 Medicine
摘要: The invention provides compounds of formula (I): or a salt thereof as described herein. also pharmaceutical compositions comprising compound I, processes for preparing (I), intermediates useful I and therapeutic methods treating the proliferation HIV virus, AIDS delaying onset ARC symptoms in mammal using (I).
lens.org参考文章(106)
Reinhard Kirsch, Jorg-Peter Kleim, Irvin Winkler, Gunther Riess, Manfred Rosner, Substituted quinoline derivatives, a process for their preparation, and their use ,(1995)
Michael A Walker, New approaches for inhibiting HIV integrase: a journey beyond the active site. Current opinion in investigational drugs. ,vol. 10, pp. 129- 136 ,(2009)
Ernest Ludwig Eliel, Samuel H. Wilen, Lewis N. Mander, Stereochemistry of Organic Compounds ,(1962)
Sybil P. Parker, McGraw-Hill dictionary of chemical terms McGraw-Hill. ,(1984)
J. F. W. McOmie, Protective Groups in Organic Chemistry ,(2012)
Raghavan Rajagopalan, John Babu, Novel quinoline-based metal chelators as antiviral agents ,(2005)
Abraham Loyter, Zvi Hayouka, Assaf Friedler, Shoshana Loya, Aviad Levin, Amnon Hizi, Joseph Rosenbluh, Moshe Kotler, Compositions and methods for inhibiting hiv-1 replication and integrase activity ,(2007)
Bruno Figadere, Eric Prina, Mohamed Fakhfakh, Alain Fournet, Reynald Hocquemiller, Xavier Franck, Substituted quinolines for the treatment of protozoan and retrovirus co-infections ,(2002)
Timothy Alan Shepherd, Louis Nickolaus Jungheim, Inhibitors of HIV protease useful for the treatment of aids ,(1993)