Angiogenesis Inhibitor Therapy in Renal Cell Cancer

作者: Sarmad Sadeghi , Brian Rini

DOI: 10.1007/978-3-642-21858-3_13

关键词: DiseaseKidney cancerClinical trialOncologyClear cell renal cell carcinomaVascular endothelial growth factorRenal cell carcinomaAngiogenesis inhibitorAngiogenesisInternal medicineMedicine

摘要: The discovery of the role angiogenesis pathways in kidney cancer has significantly changed landscape this disease, particularly metastatic setting. Medications targeting vascular endothelial growth factor (VEGF), center point pathways, have given new treatment options to patients and clinicians beyond interferon therapy. This chapter provides a review history current understanding focusing on VEGF-targeting agents currently approved for use clinical practice will end with discussion newer VEGF trials.

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