作者: Sarmad Sadeghi , Brian Rini
DOI: 10.1007/978-3-642-21858-3_13
关键词: Disease 、 Kidney cancer 、 Clinical trial 、 Oncology 、 Clear cell renal cell carcinoma 、 Vascular endothelial growth factor 、 Renal cell carcinoma 、 Angiogenesis inhibitor 、 Angiogenesis 、 Internal medicine 、 Medicine
摘要: The discovery of the role angiogenesis pathways in kidney cancer has significantly changed landscape this disease, particularly metastatic setting. Medications targeting vascular endothelial growth factor (VEGF), center point pathways, have given new treatment options to patients and clinicians beyond interferon therapy. This chapter provides a review history current understanding focusing on VEGF-targeting agents currently approved for use clinical practice will end with discussion newer VEGF trials.