An open study of buspirone augmentation of serotonin reuptake inhibitors in refractory depression.

摘要: Background: We evaluated the efficacy of buspirone in augmentation antidepressant response to serotonin reuptake inhibitors, Method: Twenty-five patients with major depressive disorder who had failed several previous treatments for their current episode were included. After failing a trial fluoxetine or fluvoxamine, they received addition inhibitor 3 weeks an open clinical trial, Results: Seventeen 25 marked complete response, Conclusion: These data provide evidence suggesting that may be useful alternative depressed fail respond