Topical Latanoprost and Optic Nerve Head and Retinal Circulation in Humans
作者： Yasuhiro Tamaki , Miyuki Nagahara , Makoto Araie , Ken Tomita , Sawako Sandoh
DOI: 10.1089/108076801753266785
关键词: Retinal 、 Intraocular pressure 、 Central retinal artery 、 Anesthesia 、 Optic nerve 、 Blood pressure 、 Medicine 、 Ophthalmology 、 Blood flow 、 Central retinal vein 、 Latanoprost
摘要: The purpose of the present study was to effect a single instillation latanoprost on human optic nerve head (ONH) and retinal circulation. Using laser-speckle tissue blood flow analysis, normalized blur (NB; quantitative index velocity) measured every 0.125 sec at temporal ONH site free visible surface vessels. Measurements were averaged for 3 cardiac cycles (NBONH). Color Doppler Imaging (CDI) also used evaluate peak systolic velocity (PSV), endo-diastolic (EDV), resistive (RI) in central artery (CRA) mean (MV) vein (CRV). One drop 0.005% instilled into one eye its vehicle other eleven healthy volunteers double-blinded manner. bilateral NBONH, CDI parameters, intraocular pressure (IOP), (BP), pulse rate (PR) performed before, 45, 90, 180, 270 min after instillation. After instill...
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