Association with Controlling Nutritional Status (CONUT) Score and In-hospital Mortality and Infection in Acute Heart Failure

作者: Takao Kato , Hidenori Yaku , Takeshi Morimoto , Yasutaka Inuzuka , Yodo Tamaki

DOI: 10.1038/S41598-020-60404-9

关键词: Body mass indexIn hospital mortalityAcute decompensated heart failureAbsolute risk reductionNutritional statusInternal medicineMedicineHeart failureConfoundingIndex hospitalization

摘要: The high controlling nutritional status (CONUT) score that represents poor has been acknowledged to have prognostic implications in chronic heart failure. We aimed investigate its role acute decompensated failure (ADHF). Using the data from an multicenter registry enrolled 4056 consecutive patients hospitalized for ADHF Japan between 2014 and 2016, we analyzed 2466 whom on components of CONUT at hospital presentation were available. decrease lymphocyte count total cholesterol was assigned with 0, 1, 2, 3 points albumin 4, 6 according severity. defined low as 0–4 (N = 1568) 5–9 (N = 898). group older more likely a smaller body mass index than those group. associated higher rate death infection during hospitalization compared (9.0% versus 4.4%, 21.9% 12.7%, respectively). After adjusting confounders, excess risk relative mortality significant (OR: 1.61, 95%CI: 1.05–2.44, OR: 1.66, 1.30–2.12, effect incremental score. High in-hospital manner ADHF.

参考文章(39)
Marc D Samsky, Chetan B Patel, Tracy A DeWald, Alastair D Smith, G Michael Felker, Joseph G Rogers, Adrian F Hernandez, None, Cardiohepatic Interactions in Heart Failure: An Overview and Clinical Implications. Journal of the American College of Cardiology. ,vol. 61, pp. 2397- 2405 ,(2013) , 10.1016/J.JACC.2013.03.042
Akira Kawamoto, Takao Kato, Eri Minamino-Muta, Yoshiaki Okano, Tetsuo Shioi, Takeshi Kimura, Relationships between nutritional status and markers of congestion in patients with pulmonary arterial hypertension. International Journal of Cardiology. ,vol. 187, pp. 27- 28 ,(2015) , 10.1016/J.IJCARD.2015.03.354
Juan Luis Bonilla-Palomas, Antonio Luis Gámez-López, Mirian Moreno-Conde, María Cristina López-Ibáñez, Manuel Anguita-Sánchez, Ángel Gallego de la Sacristana, Francisco García-Catalán, Antonia Villar-Ráez, Hypoalbuminemia in Acute Heart Failure Patients: Causes and Its Impact on Hospital and Long-Term Mortality Journal of Cardiac Failure. ,vol. 20, pp. 350- 358 ,(2014) , 10.1016/J.CARDFAIL.2014.01.016
Steve R. Ommen, Raymond J. Gibbons, David O. Hodge, Stephen P. Thomson, Usefulness of the Lymphocyte Concentration as a Prognostic Marker in Coronary Artery Disease The American Journal of Cardiology. ,vol. 79, pp. 812- 814 ,(1997) , 10.1016/S0002-9149(96)00878-8
Stefan D Anker, Piotr Ponikowski, Susan Varney, Tuan Peng Chua, Andrew L Clark, Katharine M Webb-Peploe, Derek Harrington, Wolfgang J Kox, Philip A Poole-Wilson, Andrew JS Coats, Wasting as independent risk factor for mortality in chronic heart failure The Lancet. ,vol. 349, pp. 1050- 1053 ,(1997) , 10.1016/S0140-6736(96)07015-8
Stephane Arques, Emmanuel Roux, Pascal Sbragia, Richard Gelisse, Bertrand Pieri, Pierre Ambrosi, Usefulness of serum albumin concentration for in-hospital risk stratification in frail, elderly patients with acute heart failure. Insights from a prospective, monocenter study International Journal of Cardiology. ,vol. 125, pp. 265- 267 ,(2008) , 10.1016/J.IJCARD.2007.07.094
Taro Narumi, Takanori Arimoto, Akira Funayama, Shinpei Kadowaki, Yoichiro Otaki, Satoshi Nishiyama, Hiroki Takahashi, Tetsuro Shishido, Takehiko Miyashita, Takuya Miyamoto, Tetsu Watanabe, Isao Kubota, The prognostic importance of objective nutritional indexes in patients with chronic heart failure Journal of Cardiology. ,vol. 62, pp. 307- 313 ,(2013) , 10.1016/J.JJCC.2013.05.007
Simon Stewart, Andrew Jenkins, Scot Buchan, Alistair McGuire, Simon Capewell, John J.J.V. McMurray, The current cost of heart failure to the National Health Service in the UK. European Journal of Heart Failure. ,vol. 4, pp. 361- 371 ,(2002) , 10.1016/S1388-9842(01)00198-2
Mihai Gheorghiade, Peter S. Pang, Acute Heart Failure Syndromes Journal of the American College of Cardiology. ,vol. 53, pp. 557- 573 ,(2005) , 10.1016/J.JACC.2008.10.041
Tamara B. Horwich, Adrian F. Hernandez, David Dai, Clyde W. Yancy, Gregg C. Fonarow, Cholesterol levels and in-hospital mortality in patients with acute decompensated heart failure. American Heart Journal. ,vol. 156, pp. 1170- 1176 ,(2008) , 10.1016/J.AHJ.2008.07.004