作者: Yang Yang , Wei Liu , Changming Dong
DOI:
关键词: Materials science 、 Polycaprolactone 、 Ultraviolet light 、 Chemical reaction 、 Combinatorial chemistry 、 Molecule 、 Photosensitivity 、 Preparation method 、 Polymer 、 Surface modification
摘要: The invention relates to photosensitive and targeting-functionalization polycaprolactone a preparation method thereof, belonging the technical field of polymer drugs, wherein comprises following steps of: preparing by sulfonylation reaction between 1-naphthoquinones-2-diazo-5-sulfonyl chloride; click chemical azido terminated glucose or lactose polycaprolactone. molecule synthesis with photosensitivity targeting performance prepared is finished reaction, step simple; meanwhile, provides simple effective way for controlled biomedical high polymer, can not only respond ultraviolet light, but also infrared light two-photon being generated suitable clinical application.