Methods and compositions for treating conditions of the eye
作者： Reem Z. Renno , Joan W. Miller , Evangelos S. Gragoudas
DOI:
关键词: Photodynamic therapy 、 Photochemistry 、 Cancer research 、 Photosensitizer 、 Angiostatin 、 Endostatin 、 Macular degeneration 、 Chemistry
摘要: Provided are methods and compositions for the photodynamic therapy (PDT) of ocular conditions characterized by presence unwanted choroidal neovasculature, example, neovascular age-related macular degeneration. The selectivity sensitivity PDT method can be enhanced combining with an anti-angiogenesis factor, angiostatin or endostatin, apoptosis-modulating factor. Furthermore, may further coupling a targeting moiety to photosensitizer so as target neovasculature.
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