Efficacy and safety of sound wave treatment of recurrent airway obstruction in horses.

摘要: Background: One proposed nonmedical therapy for recurrent airway obstruction (RAO) in horses is a handheld acoustic device that propels sound waves from the nose down tracheobronchial tree where it intended to dislodge mucous and relax bronchospasm, permitting clearance of mucoid secretions. Objective: To evaluate effectiveness safety this when used as per manufacturer's recommendations treatment RAO. Animals: Nine adult previously diagnosed with RAO. Methods: Prospective, cross-over clinical trial. Horses were exposed dusty environment until developed defined by standard lung mechanics (SLM). randomly assigned receive either or sham 4 weeks while being maintained environment. evaluated scores, SLM, forced expiration regularly weeks. The opposite was administered after washout period. Results: Seven received treatment; 9 sham. There no changes (P > .05) score, maximal change transpulmonary pressure (ΔPLmax), resistance (RL), expiratory flow rate averaged over last 75–95% (FEF75−95%) study period. determined be safe, although several minor adverse effects noted, including head tossing, coughing, chewing during treatment. Conclusions Clinical Importance: Treatment did not improve signs function RAO kept Currently accepted treatments, environmental management medical therapy, should recommended.