Aberrant Epithelial Cell Proliferation in Peripheral Airways in Bronchiectasis.
作者： Yang Peng , Ai-ru Xu , Shi-ying Chen , Yan Huang , Xiao-rong Han
关键词: Lung 、 Bronchiectasis 、 Epithelium 、 Progenitor cell 、 Immunostaining 、 Pathology 、 Club cell 、 Hyperplasia 、 Bronchiole 、 Medicine
摘要: Dilation of bronchi and bronchioles caused by destruction and excessive epithelial remodeling is a characteristic feature of bronchiectasis. It is not known how epithelial progenitor cells contribute to these pathologic conditions in peripheral airways (bronchioles) in bronchiectasis. We aimed to explore the expression levels of signature airway progenitor cells in the dilated bronchioles in patients with bronchiectasis. We obtained the surgically resected peripheral lung tissues from 43 patients with bronchiectasis and 33 control …
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