Oncogene-induced senescence is part of the tumorigenesis barrier imposed by DNA damage checkpoints
作者： Jirina Bartkova , Nousin Rezaei , Michalis Liontos , Panagiotis Karakaidos , Dimitris Kletsas
DOI: 10.1038/NATURE05268
关键词: DNA repair 、 Cancer research 、 DNA re-replication 、 Senescence 、 Cell cycle 、 DNA replication 、 Cell cycle checkpoint 、 DNA damage 、 G2-M DNA damage checkpoint 、 Biology
摘要: Recent studies have indicated the existence of tumorigenesis barriers that slow or inhibit the progression of preneoplastic lesions to neoplasia. One such barrier involves DNA …
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