Antibiotic prophylaxis for group A streptococcal burn wound infection is not necessary.

摘要: Background: Historically, group A beta-hemolytic streptococci (GAS) burn wound infection has been a major source of morbidity and mortality in patients prompted the prophylactic administration antibiotics to children with burns. Wound monitoring, surveillance cultures, early excision deep wounds may have changed this. Our objective this project was determine efficacy routine antibiotic prophylaxis era closure wounds. Methods: Two cohorts burned were compared: all admitted during calendar years 1992 through 1994 (group 1) 1995 1997 2). All 1 received GAS prophylaxis. Only those 2 documented positive admission or cultures for treated. Results: There 511 406 2. They well matched age (4.7 ± 0.21 vs. 5.3 0.26 years, p = 0.06) size (11.0% 0.7% 12.4% 0.8%,p 0.18). species recovered at hospitalization from 11 (2.6%) 18 (4.4%) (p 0.05), indicating marginally higher rate carriage Nevertheless, there three (0.6%) who developed four (0.98%,p 0.71). The incidence (27%) (22%) No child fulminant infection. Conclusion: Routine not effective further reducing low baseline if screening by culture is used identify carry organism burns practiced.