Loss of myeloid-specific protein phosphatase 2A enhances lung injury and fibrosis and results in IL-10-dependent sensitization of epithelial cell apoptosis.
作者： Lei Sun , Elissa M. Hult , Timothy T. Cornell , Kevin K. Kim , Thomas P. Shanley
DOI: 10.1152/AJPLUNG.00299.2018
关键词: Interleukin 10 、 Sensitization 、 Myeloid 、 Cancer research 、 Protein phosphatase 2 、 Fibrosis 、 Lung injury 、 Cytokine 、 Chemistry 、 Phosphatase
摘要: Protein phosphatase 2A (PP2A), a ubiquitously expressed Ser/Thr is an important regulator of cytokine signaling and cell function. We previously showed that myeloid-specific deletion of...
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